Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy
نویسندگان
چکیده
منابع مشابه
Macromolecular structure determination by cryo-electron microscopy.
Recent advances in transmission electron microscopy (EM) hardware, low-temperature methods and image-processing software have made cryo-EM an important complement to X-ray crystallography and NMR for macromolecular structure determination, particularly of large assemblies. This review provides a summary of the main advances and a survey of the capabilities of this approach.
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ژورنال
عنوان ژورنال: Journal of Structural Biology
سال: 2019
ISSN: 1047-8477
DOI: 10.1016/j.jsb.2018.12.001